In this article, the author seeks to understand the effect of witchcraft beliefs (both personal and regional) on various measures of social capital. Through empirical tests, the author concludes that witchcraft beliefs are robustly associated with anti-social attitudes in 19 Sub-Saharan African countries. Specifically, they find that witchcraft and other supernatural beliefs significantly affect levels of both generalized trust and trust for people of other religions. They also find that these attitudes are present among second-generation immigrants to Europe who originate from these countries. The worldwide Standard Cross-Cultural Sample is also used to examine relationships between witchcraft, mistrust, and other anti-social behaviors.